1-Benzyl-4′,5′-diphenylpiperidine-3-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-4,2′′-dione
نویسندگان
چکیده
The asymmetric unit of the title compound, C(34)H(31)N(3)O(2), consists of two independent mol-ecules which differ slightly in the orientations of the phenyl rings with respect to the pyrrolidine ring. In both mol-ecules, the piperidin-4-one ring adopts a chair conformation, whereas the pyrrolidine ring adopts an envelope conformation in one of the mol-ecules and a twisted conformation in the other. An intra-molecular C-H⋯O hydrogen bond is observed. The crystal packing is stabilized by inter-molecular N-H⋯O hydrogen bonds and C-H⋯π inter-actions.
منابع مشابه
1′-Benzyl-4,4′′-bis(4-chlorophenyl)-3-(2,6-dichlorophenyl)-1′′-methyl-4,5-dihydroisoxazole-5-spiro-3′-piperidine-5′-spiro-3′′-pyrrolidine-2′′-spiro-3′′′-indoline-2′′′,4′-dione
The asymmetric unit of the title compound, C(43)H(34)Cl(4)N(4)O(3), contains two crystallographically independent mol-ecules. In both mol-ecules, the pyrrolidine ring adopts a twist conformation, the oxindole units are slightly distorted from planarity and the isoxazoline ring adopts an envelope conformation. The crystal structure is stabilized by N-H⋯O hydrogen-bonding inter-actions giving one...
متن کامل4′-(2,4-Dichlorophenyl)-1,1′-dimethylpiperidine-3-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-4,2′′-dione
In the title compound, C(23)H(23)Cl(2)N(3)O(2), the pyrroline ring adopts an envelope conformation and the piperidinone ring assumes a slightly twisted chair form. In the crystal, inversion dimers linked by pairs of N-H⋯O hydrogen bonds generate an R(2) (8) graph-set motif and a short Cl⋯Cl contact of 3.478 (1) Å occurs.
متن کامل1′′-Benzyl-1′-methyl-4′-(naphthalen-1-yl)naphthalene-2-spiro-3′-pyrrolidine-2′-spiro-3′′-indoline-1,2′′-dione
In the title compound, C(38)H(32)N(2)O(2), the pyrrolidine ring adopts an envelope conformation, whereas the cyclo-hexa-none ring in the tetra-hydro-naphthalene fused-ring system adopts a half-chair conformation. The benzyl ring is oriented at an angle of 67.1 (1)° with respect to the naphthyl ring system. Four intra-molecular C-H⋯O close contacts and C-H⋯π inter-action are observed. In the cry...
متن کامل5′′-(4-Chlorobenzylidene)-4′-(4-chlorophenyl)-5-fluoro-1′,1′′-dimethylindoline-3-spiro-2′-pyrrolidine-3′-spiro-3′′-piperidine-2,4′′-dione
The piperidine ring of the title compound, C(30)H(26)Cl(2)FN(3)O(2), adopts a twisted chair conformation. The pyrrolidine ring has a twisted envelope structure with the N atom at the flap [displaced by 0.592 (3) Å]. The fluoro-oxindole, chloro-phenyl and chloro-benzyl-idene groups are planar with r.m.s. deviations of 0.0348, 0.0048 and 0.0048 Å, respectively. The structure is stabilized by inte...
متن کامل(1′S)-4-(3,4-Dichlorophenyl)-1′-(3,5-dimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene-2-spiro-2′-pyrrolizidine-3′-spiro-3′′-indoline-1,2′′-dione
In the title compound C(37)H(32)Cl(2)N(2)O(4), the unsubstituted pyrrolidine ring shows a twist conformation whereas the substituted pyrrolidine ring shows an envelope conformation. The dimeth-oxy benzene ring is perpendicular to the tetra-lone ring, making a dihedral angle of 89.94 (5)°. Mol-ecules are linked into centrosymmetric dimers by N-H⋯O hydrogen bonds and the crystal structure is stab...
متن کامل